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Effects of Other Medicines on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (key route) and CYP2C9 (minimal route). Consequently, inhibitors of these isoenzymes may well reduce sildenafil clearance and inducers of those isoenzymes may well maximize sildenafil clearance.På den annen aspect, mens det er den aktive ingrediensen i Via